Dr Syed Sajjad Nazir, Dr Syed Adil Bashir, Dr Naveed Khan, Dr Tanveer Iqbal, Prof Shoukat A Jeelani, Prof Muneer Khan



The most important recent advances in the managememt of ureteral calculi have been the development of medical expulsive therapy to facilitate passage of ureteral stones. Drugs like alpha 1 adrenergic blockers with or without corticosteroids along with hydration have been used to facilitate expulsion of stones.

Material & Methods :

3000 patients, from January 2008  to December 2017,  who were diagnosed to have ureteric calculi either by USG / NCCT  and presented to our OPD within first 2 days of colic were enrolled in this study. They were started with SOADS regime  which included Tab Alfa blocker ( Alfuzocin 10 mg ) once daily, Tab Drotaverine Hydrochloride 80 mg + Tab Mefenamic Acid 250 mg Twice Daily , Tab spironolactone 25 mgonce daily , Tab ofloxacin 200 mg Twice daily and Syrup Potassium magnesium citrate 2 Tsf with one glass of water three times daily with 2-3 litres of fluid for a period of 2 – 4 weeks .

Results :

 Out of 3000 pt , 2550 pts ( 85 % ) passed the stone with SOADS regime. 65 % of pt passed within 2 weeks of therapy and 20 % within 4 weeks. Stone size of 4mm, 5mm & 6 mm comprised 65 % who passed within 2 weeks and rest 20 % pts had stone size of 7mm, 8mm & 9mm. Rest of the 15 % were managed by URSL. An interesting observation was noticed that pts with obstructive stone unilaterally had increased BP of 10 mmhg both systolic and diasystolic.

Conclusion :. It is possible to facilitate explusion of ureteric calculi with SOADS  regime in patients who present within first 2 days of colic and thus avoid surgical intervention and thereby reducing the cost and lost working days.


ureteric stone, alfuzosin, medical explusive therapy.

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Yencilek F, Erturhan S, Onder C, Koyuncu H, Erol B, Sarica K.

Does Tamsulosin change the Management of proximally located Ureteric stones ?

Urological Research 2010; 38: 195-199

Sierakowski R, Finlayson B, Landes RR, Finlayson CD, Sierakowski N.

The frequency of Urolithiasis in hospital discharge diagnosis in the United States.

Invest Urol 1978; 15:438-41.

Seitz C, Liatsikos E, Porpiglia F, Tiselius HG, Zwergel U.

Medical therapy to facilitate the passage of stones : What is the evidence ?

Eur Urol 2009; 56: 455-71

Cervenakov I, Fillo J, Mardiak J, Kopecny M, Smirala J, Lepies P.

Speedy elimination of ureterolithiasis in lower part of ureters with the alpha1blocker-Tamsulosin.

Int Urol Nephrol 2002; 34: 25-9.

Hollingsworth JM, Rogers MA, Kaufman SR, Bradford TJ, Saint S, Wei JT, et al.

Medical therapy to facilitate urinary stone passage: a meta-analysis.

Lancet 2006 ; 368 : 1171-9.

Ueno A, Kawamura T, Ogawa A, Takayasu H.

Relation of spontaneous passage of ureteral calculi to size.

Urology 1977 ; 10 : 544-546.

Carstensen HE, Hansen TS.

Stones in the ureter.

Acta Chir Scand Suppl. 1973 ; 433 : 66-71.

Lotan Y, Gettman MT, Roehrborn CG.

Management of ureteric calculi: A cost comparison and decision making analysis.

J Urol 2002 ; 167 : 1621.

Cooper JT, Stack GM, and Cooper TM.

Intensive medical management of ureteral calculi.

Urology 2000; 56 : 575-8.

Tilakv M, Bhamare N.

Progesteron Hydrotherapy in Management of Small, Mid and Lower ureteric calculi.

International Journal of Recent Trends in Science and Technology 2012; 4:90-3.


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